There are three fundamental approaches for bleaching vital teeth: in-office or power bleaching, at-home or dentist supervised night-guard bleaching.

First, in-office bleaching utilizes a high concentration of tooth-whitening agents (25–40% hydrogen peroxide). Here, the dentist has complete control throughout the procedure and has the ability to stop it when the desired shade/effect is achieved. In this procedure, the whitening gel is applied to the teeth after protection of the soft tissues by rubber dam or alternatives, and the peroxide will further be activated (or not) by heat or light for around one hour in the dental office.

Second, at-home or dentist-supervised night-guard bleaching basically involves the use of a low concentration of whitening agent (10–20% carbamide peroxide).

The bleaching gel is applied to the teeth through a custom-fabricated mouthguard worn at night for at least 2 weeks.

A 35% concentration of hydrogen peroxide is recommended by some clinicians for in-office dental bleaching, followed by at-home bleaching with gels containing 10%, 15%, or 20% carbamide peroxide